Frustrated with Years of Therapy

I am 33 years old, and have been in therapy for the past 10 years. Every time I get to a point where I can deal with the REAL issues that drive my bad decisions I fall apart. Lose a job, therapist etc. I am not sure that I will ever be able to change this pattern and I am feeling hopeless, as I have tried to work with several therapists at this point with minimal results. I am not happy, and I am not making good decisions, relationships or career choices. Should I just give up and accept the fact that my prior conditioning is stronger than the healthy part of me?